Unilateral Vitiligo/Segmental Vitiligo

In some cases, cutaneous nerve damage or death can occur for unknown reasons. When this happens, the damaged nerves release certain chemicals/neurotoxins that can harm the delicate melanocytes in the skin. The body’s immune system or hyperactive immune system or aptly autoimmunity, will then eliminate these damaged cells resulting in one or few white patches limited to one side of the body but not necessarily limited to one segment. The damage of melanocytes are so much that one can have white hairs on the patch or even normal skin surrounding the patch. We have observed bi -segmental and multi segmental vitiligo in few, where two or multiple such segmental vitiligo arise in same individual.